Manufacturers of nitrofurantoin in the instructions for the drug indicate that it should not be taken by persons with heart failure (heart failure) of degrees 2 and 3, severe pathologies of the kidneys and liver, cirrhosis and hepatitis, hemodialysis, neuritis and polyneuropathies, kidney abscesses, pulmonary fibrosis . It is also contraindicated in porphyria and hypersensitivity to nitrofurans. You can not prescribe a drug to pregnant and lactating women.
If there is a safe alternative, the drug is not recommended for children under 12 years of age..
nitrofurantoin for prostatitis is not prescribed, because it penetrates poorly into the tissue of the prostate gland and does not have a bactericidal effect in full.
General properties of nitrofurans
The antibacterial effect of nitrofurans is based on several mechanisms of action:
- impaired protein synthesis in the microbial cell;
- violation of biochemical processes in the microbial cell;
- activation of peroxidation;
- destruction of the cytoplasmic membrane of pathogens.
Composition and form of release
What is nitrofurantoin? The instructions for use claim that it is a crystalline powder of orange or yellow color, which has a specific bitter taste. This compound is very poorly soluble not only in water but also in alcohol..
In what forms are drugs produced with a component such as nitrofurantoin? Reviews report that such funds are produced in the form of tablets of various dosages. They can be enteric coated or released without it..
in blister strip packaging 10 pcs.; in a pack of cardboard 2 packs.Where To Buy Nitrofurantoin 50 mg Without Prescription for Acute Cystitis.
List of drugs from the nitrofuran group
The main drugs from the group of nitofurans include:
- Nitrofural (furatsilin);
- Nitrofurantoin (Furadonin);
- Potassium furazidine (Furagin, Furamag);
- Nifuroxazide (Stopdiar, Ercefuril).